Giorgia Conta, PhD

Brief Summary

My research work is on NMR-based Metabolomics, in particular on state-of-the-art characterization of the metabolic profiles of human biofluids, animals, plants, microbes and cells, in relation to biotic or abiotic perturbations.

I have 6 years of professional experience in NMR Metabolomics, working in cross-functional teams and directly with hospitals, companies and different university departments. I am a member of NMLab, the NMR laboratory for metabolomics at Sapienza University.

📧 conta.giorgia [at] gmail.com

Research Activities

• Metabolic profiling of foods and food products;
• Evaluation of the effect of dietary interventions on human health;
• Interactions among diet, gut microbiota and host in physiological and pathological state;
• Identification of metabolic targets in different human pathologies;
• Development of personalized approaches based on the individual’s metabolic phenotype (Precision Nutrition and Medicine)

Education

Experience

Publications

Peer-reviewed accepted papers

1. “2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans” Schifano E, Conta G, Preziosi A, Ferrante C, Batignani G, Mancini P, Tomassini, Sciubba F, Scopigno T, Uccelletti D, Miccheli A. Frontiers in Molecular Biosciences, 2022.
2. “Gut microbiota functional traits, blood pH, and anti-GAD antibodies concur in the clinical characterization of T1D at onset” Del Chierico F, Conta G, Matteoli MC, Fierabracci A, Reddel S, Macari G, Gardini S, Guarrasi V, Levi Mortere S, Marzano V, Vernocchi P, Sciubba F, Marini F, Deodati A, Rapini N, Cianfarani S, Miccheli A, Putignani L. International Journal Of Molecular Sciences, 2022, https://doi.org/10.3390/ijms231810256
3. “Longitudinal multi-omics study of a mother-infant dyad from breastfeeding to weaning: an individualized approach to understand the interactions among diet, fecal metabolome and microbiota composition” Conta G, Marini F, Sciubba F, Capuani G, Tomassini A, Di Cocco ME, Miccheli A. Frontiers in Molecular Biosciences, 2021, https://doi.org/10.3389/fmolb.2021.688440.
4. “Red beetroot’s NMR-based metabolomics. Phytochemical profile related to development time and production year” Giampaoli O, Sciubba F, Conta G, Capuani G, Tomassini A, Brasili E, Miccheli A. Foods, 2021, https://doi.org/10.3390/foods10081887.
5. “Characterization of the gut-liver-muscle axis in cirrhotic patients with sarcopenia” Ponziani FR, Picca A, Marzetti E, Calvani R, Conta G, Del Chierico F, Capuani G, Faccia M, Fianchi F, Funaro B et al. Liver International, 2021, https://doi.org/10.1111/liv.14876.
6. “Can the FUT2 non-secretor phenotype associated with gut microbiota increase the children susceptibility for type 1 diabetes? A mini review.” Giampaoli O, Conta G, Calvani R, Miccheli A. Frontiers in Nutrition, 2020, https://doi.org/10.3389/fnut.2020.606171.
7. “Effects of a synbiotic formula on functional bowel disorders and gut microbiota profile during long-term home enteral nutrition (LTHEN): a pilot study.” D'Onofrio V, Del Chierico F, Belci P, Vernocchi P, Quagliariello A, Reddel S, Conta G, Mancino MV, Fadda M, Scigliano MC, Morelli R, De Francesco A, Guagnini F, Fassio F, Galletti R, Putignani L. Nutrients, 2020, https://doi.org/10.3390/nu13010087.
8. “Identification of a circulating amino acid signature in frail older persons with type 2 diabetes mellitus: results from the metabofrail study.” Calvani R, Rodriguez-Mañas L, Picca A, Marini F, Biancolillo A, Laosa O, Pedraza L, Gervasoni J, Primiano A, Conta G, Bourdel-Marchasson I, Regueme SC, Bernabei R, Marzetti E, Sinclair AJ, Gambassi G. Nutrients, 2020, https://doi.org/10.3390/nu12010199.
9. “Fused omics data models reveal gut microbiome signatures specific of inactive stage of juvenile idiopathic arthritis in pediatric patients” Vernocchi P, Marini F, Capuani G, Tomassini A, Conta G, Del Chierico F, Malattia C, De Benedetti F, Martini A, Dallapiccola B, van Dijkhuizen EHP, Miccheli A, Putignani L. Microorganisms (MDPI), 2020, https://doi.org/10.3390/microorganisms8101540.
10. “Network analysis of gut microbiome and metabolome to discover microbiota-linked biomarkers in patients affected by non-small cell lung cancer” Verrnocchi P, Gili T, Conte F, Del Chierico F, Conta G, Miccheli A, Botticelli A, Nuti M, Marchetti P, Paci P, Caldarelli G, Putignani L. International Journal Of Molecular Sciences (MDPI), 2020, https://doi.org/10.3390/ijms21228730.
11. “Targeted and untargeted metabolomics applied to occupational exposure to hyperbaric athmosphere” Tranfo G, Marchetti E, Pigini D, Miccheli A, Spagnoli M, Sciubba F, Conta G, Tomassini A, Fattorini L. Toxicology Letters, 2020, https://doi.org/10.1016/j.toxlet.2020.03.022.
12. "NMR-based metabolomics to evaluate the milk composition from Friesian and autochthonous cows of Northern Italy at different lactation times”, Tommasini A, Curone G, Solè M, Capuani G, Sciubba F, Conta G, Miccheli A, Vigo D. Natural Product Research, 2018, https://doi.org/10.1080/14786419.2018.1462183.
13. “A flow SPR immunosensor based on a sandwich direct method”, Tomassetti M, Conta G, Campanella L, Favero G, Sanzò G, Mazzei F, Antiochia R. Biosensors (MDPI), 2016, https://doi.org/10.3390/bios6020022.

Posters

1. “A multi-omics approach to investigate the role of gut microbiota metabolism and composition in a pediatric cohort at the onset of Type 1 Diabetes” 18th International Conference of the Metabolomics Society, Valencia, 19-23 June 2022
2. “NMR-based metabolomic for the evaluation of red beetroot juice effect on athletes during exercise” XXVIII National Congress of the Italian Chemical Society - Analytical Chemistry division group, Bari, 22-26 September 2019.
3. “Red beetroot’s metabolic profiling: biomarkers related to plant development, production year, juice processing and its human assumption” The 2nd Food Chemistry Conference: Shaping the Future of Food Quality, Safety, Nutrition and Health - Elsevier, Seville, 17-19 September 2019.
4. “The evolution of infant gut microbiota metabolism during the breastfeeding and weaning as investigated on a mother-infant dyad by 1H NMR-based metabolomics” Convegno Giovani Ricercatori, Rome, 25-26 June 2019.
5. “1H NMR-based metabolomic study of a mother-infant dyad on the evolution of gut microbiota during the breastfeeding and weaning” GIDRM - XLVII National Congress On Magnetic Resonance, Turin, 19-21 September, 2018.
6. “A flow SPR immunosensor based on a sandwich direct method” Settimo Convegno Giovani Chimici: le frontiere della Chimica nel nuovo millennio, Roma, 14-15 June 2016.

Oral Presentations

1. “NMR-based metabolomics and multi-block omic approach to investigate the role of gut microbiome in children with type 1 diabetes” GIDRM - XLIX National Congress On Magnetic Resonance, online, 8-10 September 2021.
2. “La metabolomica basata su NMR nello studio del microbioma intestinale nelle patologie umane” ConoScienza in Condivisione, Rome, 1 July 2021.